再生运动医学的未来展望
想象一下25年后的矫形运动医学会是什么样子。
如果一个人自己的干细胞或富含血小板的血浆可以被注射或与运动结合，以帮助病人推迟或避免关节置换——或更快地愈合——或使肌肉愈合得更强——或减少手术后的疤痕，那会怎么样?
你不用等25年。再生运动医学的未来就在现在。这些进展已经在开发中，而领导SPRI再生运动医学新中心的人是首席科学官Johnny Huard博士。
他于2015年5月1日加入SPRI。他来自加拿大魁北克，曾任匹兹堡大学肌肉骨骼细胞疗法副主席。他也是干细胞研究中心的主任和整形外科系主任亨利J.曼金教授。
他是干细胞研究领域的世界知名专家，在基因治疗、组织工程和再生医学方面拥有广泛的专业知识——所有这些都基于肌肉衍生成体干细胞的使用。
Huard博士在SPRI的任命是该研究所和德克萨斯大学休斯顿健康科学中心之间独特合作关系的一部分。
斯蒂德曼博士是先驱者
波德博士很快就承认Spri的Richard Steadman博士是这一领域的先驱，虽然它当时没有被称为再生体育医学。“博士Steadman在他的时间前面很好。他希望他的患者在手术后立即活跃。他开始记录这种方法如何有用，但没有人知道它背后的科学就是为什么工作。“
“25年后，我们的研究表明，干细胞来自血管，如果你通过锻炼增加血管的数量，你就可以增加干细胞的数量。”
“在SPRI，我们将测试我们的前提，即移植一个人自己的干细胞不会使他更年轻，但它将延缓与衰老相关的疾病，如骨关节炎和骨质疏松症。在这个过程中，我们正在学习如何让伤口愈合得更好。”
撒连接
“很久以前，我很久以前就开始对斯大尔曼诊所感兴趣，因为斯特克曼的声誉和Spri，因为它在研究中卓越。该研究所已经在进行富含血小板血浆（血浆中富含生长因子血小板）和细胞生物学的工作。““加入Spri工作人员的医生是世界上总理骨科外科医生，他们把自己放在了边缘，因为他们所做的事情是新的。”“此外，我在匹兹堡大学时，我知道菲利普博士，他通过在髋关节手术领域的巨大进步来继续努力博士遗产。”快速的台式床位博士沃德博士补充说，他决定加入Spri的工作人员的一个重要因素是它的能力迅速从研究台到患者的床边迅速采取创新的技术或治疗。“我可以给你的最好的例子是，我们现在处于临床试验，目前正在致电抗纤维化（抗疤痕）代理商，称为洛萨沙坦。腓利朋博士正准备在他的一名患者身上进行手术。我建议（通过患者的批准），他在手术后将患者放在洛沙坦。他做过，患者对治疗效果很好。在更大的机构可能无法实现那种床位到床边速度。“ FOUR INVESTIGATIONS Dr. Huard’s initial research at SPRI will focus on four investigations. The first is to evaluate the effects of exercise and neuromuscular stimulation/ massage on tissue repair after an injury. The second looks at delaying joint degeneration through the injection of adult stem cells and other biologics (medical products made from a biological source). His team wants to find the answer to the question, “Can stem cells be the ultimate body repair kit?” The third study will be a collaboration between Dr. Huard, Dr. Philippon, and Dr. Robert LaPrade, who have injected platelet-rich plasma into selected hip and knee patients to help them heal faster. The three researchers believe that combining PRP with the patient’s own stem cells in an affected joint will significantly accelerate the healing process. The fourth initiative will measure the effects of anti-fibrotic agents on tissue repair. Significantly reducing scarring in the injured tissue could create a dramatically more satisfying and faster recovery. TIMETABLES, GOALS “It is very difficult to predict exact timetables in terms of research outcomes,” says Dr. Huard, “but we may be within a year for some of the PRP applications. With stem cells, we have already seen positive results with 12 patients to repair cardiac tissue and 500 patients to reduce bladder dysfunctions. Because of advances we’ve made in other areas, we may be able to go faster in sports medicine.” Dr. Huard’s timetable for the new Regenerative Sports Medicine Laboratory at SPRI is much more specific. “By the end of the first year, we want the lab to be well funded, to be fully functional, and to have produced multiple publications to show people what we are doing.” He is also explicit in his expectations of where he wants the SPRI Center for Regenerative Sports Medicine to be in terms of world leadership. “We want people around the world to know about viable treatment options for orthopaedic injuries and conditions. Based on our interaction with other departments at SPRI, we will be able to tell patients what works, what doesn’t work, and explain the reasons why. The Center will be a place where we make treatments better and safer for our patients.” In the long term, Dr. Huard envisions every person having the opportunity to harvest his or her own stem cells, preferably at a young age. The cells could be frozen, stored, and then re-injected later to help those people age better, enjoy an active life, and get the best treatment when they need it. Although it may take 10 years to perfect, the procedure could literally slow down the aging process. Dr. Huard brings an unparalleled record of achievements, publications, and awards to the Steadman Philippon Research Institute. With your support, there is every reason to believe that he, his team, and his colleagues at SPRI represent the future of regenerative sports medicine to the rest of the world.